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KMID : 0374019940170040363
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Ewha Medical Journal
1994 Volume.17 No. 4 p.363 ~ p.370
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Retinal Changes after Replacement of Vitreous with Perfluorodecalin
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Abstract
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Retinal changes were evaluated after vitreous replacement with perfluorodecalin. Tolerance to this liquid in rabbit eyes was investigated for period of 1 month.
Histologic examination revealed degeneration and loss of the outer segment of the photoreceptors, decreased thickness of the outer retinal layers and the appearance of the macrophages with clear cytoplasmic vacuoles on the surface of retina and
in
the
vitreous. These changes were progressed with the longer duration of the intravitreal replacement of perflurodecalin. From the above results, perfluorodecalin is thought to be unsuitable for the long-term vitreous substitute and be removed from
the
eye
before the completion of surgery.
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